Umbilical cord stem cells advantages and disadvantages

Umbilical cord stem cells come from the umbilical cord and placenta blood following birth. They can only be harvested after birth and can be stored for later use in other medical applications. This collection does not change the birth and it is safe for both mother and baby. But there are some Umbilical cord stem cells advantages and disadvantages.

Umbilical cord blood stems cells are used to treat about 80 health conditions, and also used in experimental treatments for cerebral palsy and Type I Diabetes. These stem cells have the capability to renew and become specialized in the repair or replacement of damaged and diseased cells.

Stem Cells “Building blocks of the body”

Stem cells are the building blocks of the body. Stem cells are capable of dividing for long periods of time, are unspecialized, but can develop into specialized cells.

A stem cell is pluripotent, When a stem cell divides, it can make any one of the 220 different cells in the human body. Stem cells also have the capability to self-renew. They can reproduce themselves many times over.

There are several types of stem cells:

  • Embryonic stem cells
    Embryonic stem cells include those found in the embryo, the umbilical cord blood depending upon when they are harvested, embryonic stem cells can give rise to any cell in the human body.
  • Adult stem cells
    Adult stem cells can be found in infants, children and adults. They reside in already developed tissues such as heart, brain and kidney, And they usually give rise to cells within their resident organs.
  • Induced pluripotent stem cells (IPSC)
    These stem cells are adult differentiated cells that have been experimentally “reprogrammed” into a stem cell like state in leb.

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Umbilical Cord Blood Stem Cells

Cord-blood bank means the bank that collects and stores the blood from within the umbilical cord (the part of the placenta that delivers nutrients to a fetus) after a baby is born.

Cord blood contains blood-forming stem cells. Which are very useful for treating diseases that require stem cell transplants (also called bone marrow transplants), such as certain kinds of leukemia or lymphoma, aplastic anemia, severe sickle cell disease, and severe combined immunodeficiency the value of cord blood stem cells over bone marrow.

Umbilical cord stem cells advantages and disadvantages

There are some Umbilical cord stem cells advantages and disadvantages:-

Umbilical cord stem cells Advantages:-

  1. No ethical, religious, or political controversies.
  2. have the potential to treat a variety of blood diseases
  3. matches the recipient more closely
  4. less chance of rejection
  5. ready supply and does not harm mother or baby
  6. Collection procedure is totally safe and noninvasive
  7. Abundant supply.
  8. Low viral contamination.
  9. Ability to store cord blood units in cord blood banks.
  10. No risk of teratoma formation.
  11. Lower risk of graft v/s host diseases (GvHD).
  12. Tolerance of HLA mismatching.
  13. Higher proliferation capacity compared with adult stem cells.

Umbilical cord stem cells Disadvantages:-

  1. The limited number of stem cells per single cord blood unit.
  2. there is not enough to treat an adult with one collection
  3. once transplanted, no more cells can be harvested from that source
  4. cord blood stem cells require more time to graft than bone marrow transplants
  5. no nationwide system for collection and storage of donated cord blood

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Advantages & Disadvantages of Other Stem Cell Sources

Sources of Stem CellAdvantagesDisadvantages
Embryonic Stem Cell1. can differentiate into any cell type in the body.
2. Serve as a strong platform for pluripotency, developmental, and lineage commitment studies.
1. Ethical, religious and political concerns.
2. the Limited number of cells isolated from each embryo.
3. High chance of transformation into cancer cells (teratomas).
4. Cells instability in-vitro due to lack of proper imprinting patterns.
Adult Stem Cell1.No ethical, religious, or political controversies.
2. Effective in generation their tissue of origin.
3. No risk of teratoma formation
4. Established clinical history.
1. Often invasive collection procedure.
2. Limited cell numbers in human body tissues.
3. Limited differentiation capabilities.
4. Limited supply.
5. Limited availability of HLA – match donors.

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Related Questions to-

(Umbilical cord stem cells advantages and disadvantages)

What are the benefits of umbilical cord stem cells?

The umbilical cord fluid is loaded with stem cells. They can treat cancer, blood diseases like anemia, and some immune system disorders, and also others, which disrupt your body’s ability to defend itself.

Do umbilical cord stem cells work?

It’s common for doctors who perform regenerative medicine therapy to take an adult’s stem cells from a patient’s blood, fat tissue, or bone marrow. But umbilical cord blood actually is a better source for the supercells that can stimulate healing and turn into new tissue.

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How much does it cost to store stem cells from the umbilical cord?

Public cord blood banking is free, but you need to pay for private banking. You can expect to pay between $1350 and $2350 for collecting, testing, and registering. You’ll also pay $100 to $175 annually for storage and maintenance fees.

What are the advantages and disadvantages of umbilical blood and adult tissue as alternative sources of stem cells?

(Umbilical cord stem cells advantages and disadvantages)

Is stem cells of the umbilical cord works on the cure of enlarged heart in new born baby?

Is stem cells of the umbilical cord works on the enlarged heart of a newly born baby?

Why stem cells are bad?

One of the bad things about stem cells is that they have been over-hyped by the media in regard to their readiness for treating multiple diseases as supercells.

What are the negative effects of stem cell therapy?

Stem Cell or Bone Marrow Transplant Side Effects-

  • Mouth and throat pain
  • Nausea and vomiting
  • Infection
  • Bleeding and transfusions
  • Interstitial pneumonitis and other lung problems
  • Graft-versus-host disease
  • Hepatic veno-occlusive disease (VOD)
  • Graft failure

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Is stem cell treatment painful?

(Umbilical cord stem cells advantages and disadvantages)

What diseases can be cured with stem cells?

(Umbilical cord stem cells advantages and disadvantages)

What country is best for stem cell treatment?

Countries like Japan and Singapore are both seen as leaders in stem cell therapies.

Why is stem cell so expensive?

Because they are not covered by medical insurance. The cost of platelet-rich therapy (PRP), which can be used separately or in conjunction with stem cell therapy.

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How long do stem cell injections last?

stem cell injections can potentially provide relief for up to one year. But some patients report the effects of treatment lasting for several years.

In what countries is stem cell therapy legal?

(Umbilical cord stem cells advantages and disadvantages)

What countries do not allow stem cells?

Germany, Austria, Italy, Finland, Ireland, Portugal, and the Netherlands prohibit or severely restrict the use of embryonic stem cells, Greece, Sweden, Spain, and the United Kingdom have created the legal basis to support this research. Belgium bans reproductive cloning but allows therapeutic cloning of embryos.

Are stem cells illegal?

No stem cell administration to humans is permissible outside the purview of clinical trials.

Where do you get stem cells from?

Stem cells get from two main sources: adult body tissues and embryos. Scientists are also working on ways to develop stem cells from other genetic “reprogramming” techniques.

Sources of stem cells-

  1. the brain.
  2. bone marrow.
  3. blood and blood vessels.
  4. skeletal muscles.
  5. skin.
  6. the liver.

If you have any doubt then you can visit the National Library of Medicine. This is a trusted government site, so you can get the benefit from it.

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